Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis
Hypoxia is known to promote tumor progression. Here, the authors evaluate hypoxic cells using a fate mapping approach and identify a distinct gene expression profile of cells exposed to intratumoral hypoxia and show that post-hypoxic tumor cells have an ROS-resistant phenotype enabling metastasis in...
Enregistré dans:
Auteurs principaux: | Inês Godet, Yu Jung Shin, Julia A. Ju, I Chae Ye, Guannan Wang, Daniele M. Gilkes |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/a5f1f8419ccf4c21aec6a8ada0d7c50b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Post-Hypoxic Cells Promote Metastatic Recurrence after Chemotherapy Treatment in TNBC
par: Inês Godet, et autres
Publié: (2021) -
Elemene Nanoemulsion Inhibits Metastasis of Breast Cancer by ROS Scavenging
par: Han B, et autres
Publié: (2021) -
Impact of the hypoxic phenotype on the uptake and efflux of nanoparticles by human breast cancer cells
par: William J. Brownlee, et autres
Publié: (2018) -
The Fate of the Scientist, the Fate of Science
par: E. B. Rashkovsky
Publié: (2012) -
Fate mapping identifies the origin of SHF/AHF progenitors in the chick primitive streak.
par: Esther Camp, et autres
Publié: (2012)