Structural basis of homo- and heterotrimerization of collagen I

Structural basis of homo- and heterotrimerization of collagen I

Heterotrimers of collagen I (two α1 chains, one α2 chain) are crucial for the normal function of multiple tissues and organs. Here the authors show the molecular basis of both homotrimerization (three α1 chains) and heterotrimerization of collagen I through specific intermolecular interactions.

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Auteurs principaux: Urvashi Sharma, Loïc Carrique, Sandrine Vadon-Le Goff, Natacha Mariano, Rainier-Numa Georges, Frederic Delolme, Peppi Koivunen, Johanna Myllyharju, Catherine Moali, Nushin Aghajari, David J. S. Hulmes
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/a60a8ed5f31b4d4886df090a13228cae
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Internet

https://doaj.org/article/a60a8ed5f31b4d4886df090a13228cae

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