Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

To comprehend the genetic regulatory mechanisms underlying brain-related traits in humans, Qi et al. estimate the correlation of expression and DNA methylation QTL effects in cis between blood and brain and show that using blood eQTL/mQTL data of large sample size  can increase power in gene discove...

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Autores principales: Ting Qi, Yang Wu, Jian Zeng, Futao Zhang, Angli Xue, Longda Jiang, Zhihong Zhu, Kathryn Kemper, Loic Yengo, Zhili Zheng, eQTLGen Consortium, Riccardo E. Marioni, Grant W. Montgomery, Ian J. Deary, Naomi R. Wray, Peter M. Visscher, Allan F. McRae, Jian Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/a6120d781df04a21806a6667b60aa876
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https://doaj.org/article/a6120d781df04a21806a6667b60aa876

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