Aberrant Intracellular pH Regulation Limiting Glyceraldehyde-3-Phosphate Dehydrogenase Activity in the Glucose-Sensitive Yeast <italic toggle="yes">tps1</italic>Δ Mutant
ABSTRACT Whereas the yeast Saccharomyces cerevisiae shows great preference for glucose as a carbon source, a deletion mutant in trehalose-6-phosphate synthase, tps1Δ, is highly sensitive to even a few millimolar glucose, which triggers apoptosis and cell death. Glucose addition to tps1Δ cells causes...
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Autores principales: | Frederik Van Leemputte, Ward Vanthienen, Stefanie Wijnants, Griet Van Zeebroeck, Johan M. Thevelein |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
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Acceso en línea: | https://doaj.org/article/a635266183c74eef89fb5533e010461d |
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