Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression

Abstract Mitochondrial respiration plays a crucial role in determining the metabolic state of brown adipose tissue (BAT), due to its direct roles in thermogenesis, as well as through additional mechanisms. Here, we show that respiration-dependent retrograde signaling from mitochondria to nucleus con...

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Bibliographic Details
Main Authors: Minwoo Nam, Thomas E. Akie, Masato Sanosaka, Siobhan M. Craige, Shashi Kant, John F. Keaney Jr, Marcus P. Cooper
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/a66f49441c9b45cab90f279e62a62661
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