Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases
Bacterial two-component systems are composed of a sensor histidine kinase (HK) and an effector response regulator and upon signal detection, the HK autophosphorylates a conserved His residue. Here the authors structurally and functionally characterise two HKs, HK853–RR468 and EnvZ–OmpR, and find tha...
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Main Authors: | Cristina Mideros-Mora, Laura Miguel-Romero, Alonso Felipe-Ruiz, Patricia Casino, Alberto Marina |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/a680d0f7de9a49d3bb3359801876a0f3 |
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