Bile acid-independent protection against Clostridioides difficile infection.

Clostridioides difficile infections occur upon ecological / metabolic disruptions to the normal colonic microbiota, commonly due to broad-spectrum antibiotic use. Metabolism of bile acids through a 7α-dehydroxylation pathway found in select members of the healthy microbiota is regarded to be the pro...

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Autores principales: Andrea Martinez Aguirre, Nazli Yalcinkaya, Qinglong Wu, Alton Swennes, Mary Elizabeth Tessier, Paul Roberts, Fabio Miyajima, Tor Savidge, Joseph A Sorg
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/a68d3cc2a7c4485c800df500d3fb295e
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