Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast.

Doxorubicin is an anthracycline antibiotic that is among one of the most commonly used chemotherapeutic agents in the clinical setting. The usage of doxorubicin is faced with many problems including severe side effects and chemoresistance. To overcome these challenges, it is important to gain an und...

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Autores principales: Zoey Tay, Ru Jun Eng, Kenichi Sajiki, Kim Kiat Lim, Ming Yi Tang, Mitsuhiro Yanagida, Ee Sin Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a69922088536450aafc248adcf8dc987
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