Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo

Photocaged inositol-pyrophosphates offer a tool to study cellular signalling, but their challenging synthesis has precluded any biological studies so far. Here, the authors report the synthesis and cellular delivery of a photocaged analogue, and show that it mediates protein translocation in cellulo...

Full description

Saved in:
Bibliographic Details
Main Authors: Igor Pavlovic, Divyeshsinh T. Thakor, Jessica R. Vargas, Colin J. McKinlay, Sebastian Hauke, Philipp Anstaett, Rafael C. Camuña, Laurent Bigler, Gilles Gasser, Carsten Schultz, Paul A. Wender, Henning J. Jessen
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/a6bac542d07b431a964d07a618a8a4d6
Tags: Add Tag
No Tags, Be the first to tag this record!