Mature IgDlow/- B cells maintain tolerance by promoting regulatory T cell homeostasis

B cells produce antibodies to mediate various immune functions, but are also reported to negatively regulate immune responses. Here, the authors show that a subset of mature B cells expressing low levels of IgD, present in both mice and human, may pursue this regulatory function indirectly by induci...

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Bibliographic Details
Main Authors: Avijit Ray, Mohamed I. Khalil, Kirthi L. Pulakanti, Robert T. Burns, Cody J. Gurski, Sreemanti Basu, Demin Wang, Sridhar Rao, Bonnie N. Dittel
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/a6be2f1b8c89426188dea0ff476a0e02
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