Multi-functional DNA nanostructures that puncture and remodel lipid membranes into hybrid materials

DNA nanopores can span lipid bilayers but how they interact with lipids is not known. Here the authors establish at single-molecule level the insertion mechanism and show that DNA nanopores can locally cluster and remodel membranes, and stabilize autonomously formed lipid nanotubes.

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Auteurs principaux: Oliver Birkholz, Jonathan R. Burns, Christian P. Richter, Olympia E. Psathaki, Stefan Howorka, Jacob Piehler
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/a70c150306da4a7bb1f6a39c57387551
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