Multi-functional DNA nanostructures that puncture and remodel lipid membranes into hybrid materials

DNA nanopores can span lipid bilayers but how they interact with lipids is not known. Here the authors establish at single-molecule level the insertion mechanism and show that DNA nanopores can locally cluster and remodel membranes, and stabilize autonomously formed lipid nanotubes.

Saved in:
Bibliographic Details
Main Authors: Oliver Birkholz, Jonathan R. Burns, Christian P. Richter, Olympia E. Psathaki, Stefan Howorka, Jacob Piehler
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/a70c150306da4a7bb1f6a39c57387551
Tags: Add Tag
No Tags, Be the first to tag this record!