Ten-eleven translocation-2 affects the fate of cells and has therapeutic potential in digestive tumors

Ten-eleven translocation (TET) methylcytosine dioxygenases catalyze the oxidative reactions of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC), and 5-carboxylcytosine (5-caC), which are intermediate steps during DNA demethylation. It is reported that somatic mutat...

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Bibliographic Details
Main Authors: Feng Wang, Jing Zhang, Jian Qi
Format: article
Language:EN
Published: KeAi Communications Co., Ltd. 2019
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Online Access:https://doaj.org/article/a7160c3dd193443da4a0086f24947baa
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