NMR monitoring of the SELEX process to confirm enrichment of structured RNA
Abstract RNA aptamers are RNA molecules that bind to a target molecule with high affinity and specificity using uniquely-folded tertiary structures. RNA aptamers are selected from an RNA pool typically comprising up to 1015 different sequences generated by iterative steps of selection and amplificat...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2017
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/a719e1e805e04e56860ef285c5f3fcd1 |
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