Ultradeep sequencing of a human ultraconserved region reveals somatic and constitutional genomic instability.

Early detection of cancer-associated genomic instability is crucial, particularly in tumour types in which this instability represents the essential underlying mechanism of tumourigenesis. Currently used methods require the presence of already established neoplastic cells because they only detect cl...

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Autores principales: Anna De Grassi, Cinzia Segala, Fabio Iannelli, Sara Volorio, Lucio Bertario, Paolo Radice, Loris Bernard, Francesca D Ciccarelli
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/a730e1a1740b4efb8d7ae0a0e570542d
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