Ultradeep sequencing of a human ultraconserved region reveals somatic and constitutional genomic instability.
Early detection of cancer-associated genomic instability is crucial, particularly in tumour types in which this instability represents the essential underlying mechanism of tumourigenesis. Currently used methods require the presence of already established neoplastic cells because they only detect cl...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Acceso en línea: | https://doaj.org/article/a730e1a1740b4efb8d7ae0a0e570542d |
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