Comprehensive Essentiality Analysis of the <italic toggle="yes">Mycobacterium tuberculosis</italic> Genome via Saturating Transposon Mutagenesis
ABSTRACT For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, these studies have analyzed subsaturated libraries, n...
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Autores principales: | Michael A. DeJesus, Elias R. Gerrick, Weizhen Xu, Sae Woong Park, Jarukit E. Long, Cara C. Boutte, Eric J. Rubin, Dirk Schnappinger, Sabine Ehrt, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/a77bd7f0cb4b428b9bb78ab3fcebcc71 |
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