Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death

por Laure Botella, Julien Vaubourgeix, Jonathan Livny, Dirk Schnappinger
Publicado 2017

Triosephosphate Isomerase Is Dispensable <italic toggle="yes">In Vitro</italic> yet Essential for <named-content content-type="genus-species">Mycobacterium tuberculosis</named-cont...

por Carolina Trujillo, Antje Blumenthal, Joeli Marrero, Kyu Y. Rhee, Dirk Schnappinger, Sabine Ehrt
Publicado 2014

Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection

por Tiago Beites, Robert S. Jansen, Ruojun Wang, Adrian Jinich, Kyu Y. Rhee, Dirk Schnappinger, Sabine Ehrt
Publicado 2021

Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis

por Rinki Chauhan, Janani Ravi, Pratik Datta, Tianlong Chen, Dirk Schnappinger, Kevin E. Bassler, Gábor Balázsi, Maria Laura Gennaro
Publicado 2016

An improved statistical method to identify chemical-genetic interactions by exploiting concentration-dependence.

por Esha Dutta, Michael A DeJesus, Nadine Ruecker, Anisha Zaveri, Eun-Ik Koh, Christopher M Sassetti, Dirk Schnappinger, Thomas R Ioerger
Publicado 2021

Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.

por Ravikiran M Raju, Mark P Jedrychowski, Jun-Rong Wei, Jessica T Pinkham, Annie S Park, Kathryn O'Brien, German Rehren, Dirk Schnappinger, Steven P Gygi, Eric J Rubin
Publicado 2014

Comprehensive Essentiality Analysis of the <italic toggle="yes">Mycobacterium tuberculosis</italic> Genome via Saturating Transposon Mutagenesis

por Michael A. DeJesus, Elias R. Gerrick, Weizhen Xu, Sae Woong Park, Jarukit E. Long, Cara C. Boutte, Eric J. Rubin, Dirk Schnappinger, Sabine Ehrt, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger
Publicado 2017

Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development

por Tiago Beites, Kathryn O’Brien, Divya Tiwari, Curtis A. Engelhart, Shaun Walters, Jenna Andrews, Hee-Jeong Yang, Michelle L. Sutphen, Danielle M. Weiner, Emmanuel K. Dayao, Matthew Zimmerman, Brendan Prideaux, Prashant V. Desai, Thierry Masquelin, Laura E. Via, Véronique Dartois, Helena I. Boshoff, Clifton E. Barry, Sabine Ehrt, Dirk Schnappinger
Publicado 2019