Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.

par Ravikiran M Raju, Mark P Jedrychowski, Jun-Rong Wei, Jessica T Pinkham, Annie S Park, Kathryn O'Brien, German Rehren, Dirk Schnappinger, Steven P Gygi, Eric J Rubin
Publié 2014

Target Mechanism-Based Whole-Cell Screening Identifies Bortezomib as an Inhibitor of Caseinolytic Protease in Mycobacteria

par Wilfried Moreira, Grace J. Y. Ngan, Jian Liang Low, Anders Poulsen, Brian C. S. Chia, Melgious J. Y. Ang, Amelia Yap, Justina Fulwood, Umayal Lakshmanan, Jolander Lim, Audrey Y. T. Khoo, Horst Flotow, Jeffrey Hill, Ravikiran M. Raju, Eric J. Rubin, Thomas Dick
Publié 2015