RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells.

RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells.

Human pancreatic ductal adenocarcinoma (PDAC) is characterized by early systemic dissemination. Although RhoC has been implicated in cancer cell migration, the relevant underlying molecular mechanisms remain unknown. RhoC has been implicated in the enhancement of cancer cell migration and invasion,...

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Autores principales: Ningfeng Fiona Li, Emilios Gemenetzidis, Francis J Marshall, Derek Davies, Yongwei Yu, Kristopher Frese, Fieke E M Froeling, Adam K Woolf, Roger M Feakins, Yoshiki Naito, Christine Iacobuzio-Donahue, David A Tuveson, Ian R Hart, Hemant M Kocher
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a7851622b51a4c94929963ab893e4540
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