Improved production process for native outer membrane vesicle vaccine against Neisseria meningitidis.

An improved detergent-free process has been developed to produce vaccine based on native outer membrane vesicles (NOMV) against Neisseria meningitidis serogroup B. Performance was evaluated with the NonaMen vaccine concept, which provides broad coverage based on nine distinct PorA antigens. Scalable...

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Autores principales: Bas van de Waterbeemd, Gijsbert Zomer, Patricia Kaaijk, Nicole Ruiterkamp, René H Wijffels, Germie P J M van den Dobbelsteen, Leo A van der Pol
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a7aca8616ff141fd93cc85f4a668c728
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