Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin

The cofilin family proteins are actin disassembly factors but the disassembly mechanism is poorly understood. Here authors show that cyclase-associated-protein (CAP) works in synergy with cofilin to accelerate actin filament depolymerization by nearly 100-fold and reveal how CAP destabilizes the int...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tommi Kotila, Hugo Wioland, Giray Enkavi, Konstantin Kogan, Ilpo Vattulainen, Antoine Jégou, Guillaume Romet-Lemonne, Pekka Lappalainen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/a7e7c8a65f604e56a1377651d6ef54c8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!