Overcoming the thermodynamic equilibrium of an isomerization reaction through oxidoreductive reactions for biotransformation

A desired product cannot be obtained at higher concentration than its equilibrium concentration when isomerases are used for biotransformation. Here, the authors engineer in vivo oxidoreductive reactions in yeast to overcome the equilibrium limitation of in vitro isomerases-based tagatose production...

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Autores principales: Jing-Jing Liu, Guo-Chang Zhang, Suryang Kwak, Eun Joong Oh, Eun Ju Yun, Kulika Chomvong, Jamie H. D. Cate, Yong-Su Jin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a7eb7182bd4e490ca187e05c77980ea5
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