Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide
Human leukocyte antigen (HLA) presents peptides to activate T cells, but many aspects in the T cell receptor (TCR)/HLA interaction remain unclear. Here the authors show, via structural data, that two TCRs differentially recognize the same tumour peptide/HLA complex and induce contrasting conformatio...
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Main Authors: | , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/a7ed25c4fcb740c1b5d4980f12c82203 |
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