ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen
ABSTRACT: Sex differences in immune-mediated diseases are linked to the activity of estrogens on innate immunity cells, including macrophages. Tamoxifen (TAM) is a selective estrogen receptor modulator (SERM) used in estrogen receptor-alpha (ERα)-dependent breast cancers and off-target indications s...
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Auteurs principaux: | , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Elsevier
2021
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Accès en ligne: | https://doaj.org/article/a7edf7f586f44f0282507cf6c6d73aa5 |
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