Intracellular delivery of lipopolysaccharide induces effective Th1-immune responses independent of IL-12.

Lipopolysaccharide (LPS) is responsible for many of the inflammatory responses and pathogenic effects of Gram-negative bacteria, however, it also induces protective immune responses. LPS induces the production of inflammatory cytokines such as TNF-α, IL-6, and IL-12 from dendritic cells (DCs) and ma...

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Autores principales: Sachiko Watanabe, Joe Inoue
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a7efb29cf55b4887a81f5a98f4557a3c
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