Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target

Attempts to image activated macrophages in vivo have been hampered by selectivity and delivery problems. Here the authors develop a small molecule fluorescent probe specific to activated M1 and M2 macrophages, identify the orphan receptor Slc18b1/SLC18B1 as the mechanism of uptake, and use it to ima...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sung-Jin Park, Beomsue Kim, Sejong Choi, Sivaraman Balasubramaniam, Sung-Chan Lee, Jung Yeol Lee, Heon Seok Kim, Jun-Young Kim, Jong-Jin Kim, Yong-An Lee, Nam-Young Kang, Jin-Soo Kim, Young-Tae Chang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/a80a5a7ec76b4b3aaca86bee713b6628
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!