TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth
Acetylation of microtubules (MT) confers mechanical stability necessary for numerous cellular functions but its regulation is unclear. Here the authors show that the MT acetyltransferase αTAT1 is regulated by TGF-β-activated kinase 1 implicating TGF-β signaling in MT-related functions and disease....
Guardado en:
Autores principales: | Nirav Shah, Sanjay Kumar, Naveed Zaman, Christopher C. Pan, Jeffrey C. Bloodworth, Wei Lei, John M. Streicher, Nadine Hempel, Karthikeyan Mythreye, Nam Y. Lee |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/a82d270420fc4d0b91e4bda9d9eca3d2 |
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