Synergy between Cyclase-associated protein and Cofilin accelerates actin filament depolymerization by two orders of magnitude

Cellular actin networks can be rapidly disassembled and remodeled in a few seconds, yet in vitro actin filaments depolymerize over minutes. Here the authors show that Cyclase-associated protein (CAP) and Cofilin synergize to processively depolymerize actin filament pointed ends 330-fold faster than...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Shashank Shekhar, Johnson Chung, Jane Kondev, Jeff Gelles, Bruce L. Goode
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/a85eeae229464d918654826b7dd93a43
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!