Tissue-specific 5-hydroxymethylcytosine landscape of the human genome

Charting the landscape of 5hmC in human tissues is fundamental to understanding its regulatory functions. Here, we systematically profiled the whole-genome 5hmC landscape at single-base resolution for 19 types of human tissues and found 5hmC shows tissue-specific patterns.

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Autores principales: Bo He, Chao Zhang, Xiaoxue Zhang, Yu Fan, Hu Zeng, Jun’e Liu, Haowei Meng, Dongsheng Bai, Jinying Peng, Qian Zhang, Wei Tao, Chengqi Yi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a881fb687b21471b850c6a144a8cec64
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