Tissue-specific 5-hydroxymethylcytosine landscape of the human genome

Charting the landscape of 5hmC in human tissues is fundamental to understanding its regulatory functions. Here, we systematically profiled the whole-genome 5hmC landscape at single-base resolution for 19 types of human tissues and found 5hmC shows tissue-specific patterns.

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Autores principales:	Bo He, Chao Zhang, Xiaoxue Zhang, Yu Fan, Hu Zeng, Jun’e Liu, Haowei Meng, Dongsheng Bai, Jinying Peng, Qian Zhang, Wei Tao, Chengqi Yi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a881fb687b21471b850c6a144a8cec64
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spelling	oai:doaj.org-article:a881fb687b21471b850c6a144a8cec642021-12-02T17:01:21ZTissue-specific 5-hydroxymethylcytosine landscape of the human genome10.1038/s41467-021-24425-w2041-1723https://doaj.org/article/a881fb687b21471b850c6a144a8cec642021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24425-whttps://doaj.org/toc/2041-1723Charting the landscape of 5hmC in human tissues is fundamental to understanding its regulatory functions. Here, we systematically profiled the whole-genome 5hmC landscape at single-base resolution for 19 types of human tissues and found 5hmC shows tissue-specific patterns.Bo HeChao ZhangXiaoxue ZhangYu FanHu ZengJun’e LiuHaowei MengDongsheng BaiJinying PengQian ZhangWei TaoChengqi YiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bo He Chao Zhang Xiaoxue Zhang Yu Fan Hu Zeng Jun’e Liu Haowei Meng Dongsheng Bai Jinying Peng Qian Zhang Wei Tao Chengqi Yi Tissue-specific 5-hydroxymethylcytosine landscape of the human genome
description	Charting the landscape of 5hmC in human tissues is fundamental to understanding its regulatory functions. Here, we systematically profiled the whole-genome 5hmC landscape at single-base resolution for 19 types of human tissues and found 5hmC shows tissue-specific patterns.
format	article
author	Bo He Chao Zhang Xiaoxue Zhang Yu Fan Hu Zeng Jun’e Liu Haowei Meng Dongsheng Bai Jinying Peng Qian Zhang Wei Tao Chengqi Yi
author_facet	Bo He Chao Zhang Xiaoxue Zhang Yu Fan Hu Zeng Jun’e Liu Haowei Meng Dongsheng Bai Jinying Peng Qian Zhang Wei Tao Chengqi Yi
author_sort	Bo He
title	Tissue-specific 5-hydroxymethylcytosine landscape of the human genome
title_short	Tissue-specific 5-hydroxymethylcytosine landscape of the human genome
title_full	Tissue-specific 5-hydroxymethylcytosine landscape of the human genome
title_fullStr	Tissue-specific 5-hydroxymethylcytosine landscape of the human genome
title_full_unstemmed	Tissue-specific 5-hydroxymethylcytosine landscape of the human genome
title_sort	tissue-specific 5-hydroxymethylcytosine landscape of the human genome
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a881fb687b21471b850c6a144a8cec64
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Tissue-specific 5-hydroxymethylcytosine landscape of the human genome

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