Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry

Summary: Type 2 diabetes mellitus (T2D) is a chronic age-related disorder characterized by hyperglycemia due to the failure of pancreatic beta cells to compensate for increased insulin demand. Despite decades of research, the pathogenic mechanisms underlying T2D remain poorly defined. Here, we use i...

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Autores principales: Minghui Wu, Michelle Y.Y. Lee, Varun Bahl, Daniel Traum, Jonathan Schug, Irina Kusmartseva, Mark A. Atkinson, Guanjie Fan, Klaus H. Kaestner
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/a8c0452dd1184df08e2878403748613b
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