Engineering rules that minimize germline silencing of transgenes in simple extrachromosomal arrays in C. elegans

C. elegans has strong repressive mechanisms that silence transgenes in the germline. Here the authors elucidate the design rules for efficient germline expression.

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Bibliographic Details
Main Authors: Mohammed D. Aljohani, Sonia El Mouridi, Monika Priyadarshini, Amhed M. Vargas-Velazquez, Christian Frøkjær-Jensen
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/a8c5b4807bab427487293c18ed3e5c8d
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