Genotypic Differences in Dengue Virus Neutralization Are Explained by a Single Amino Acid Mutation That Modulates Virus Breathing
ABSTRACT Flaviviruses sample an ensemble of virion conformations resulting from the conformational flexibility of their structural proteins. To investigate how sequence variation among strains impacts virus breathing, we performed studies with the monoclonal antibody (MAb) E111, which binds an inacc...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2015
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| Accès en ligne: | https://doaj.org/article/a8d04135145e4f91b260faa27f5d3516 |
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