The N terminus of orf virus-encoded protein 002 inhibits acetylation of NF-κB p65 by preventing Ser(276) phosphorylation.
Orf virus-encoded protein 002 (ORFV002) inhibits NF-κB signaling pathway by decreasing the acetylation of NF-κB-p65 through interference of NF-κB p65's association with NF-κB p300. However, the precise mechanism of how ORFV002 interferes with the NF-κB p65/p300 association is still unknown. Due...
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Main Authors: | Zhangyong Ning, Zewei Zheng, Wenbo Hao, Chaohui Duan, Wei Li, Yuanyuan Wang, Ming Li, Shuhong Luo |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/a8d2b3ce84804c28a507bd7053c1e5c9 |
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