Durable targeting of B-lymphocytes in living mice
Abstract Transfer to and enduring expression of genes in B cells has proved a vexing challenge. We report here a novel method for the specific and durable targeting of B lymphocytes in living mice. The method involves generation of lentiviruses pseudotyped with an anti-CD19 antibody. CD19 targeting...
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Autores principales: | M. Cascalho, D. Huynh, A. R. Lefferts, L. Stein, T. Lanigan, J. Decker, L. D. Shea, J. L. Platt |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/a8d8bc5a0ace45508e8d50d4287059cd |
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