Premitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic state.
Centromeres are differentiated chromatin domains, present once per chromosome, that direct segregation of the genome in mitosis and meiosis by specifying assembly of the kinetochore. They are distinct genetic loci in that their identity in most organisms is determined not by the DNA sequences they a...
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Main Authors: | , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/a8dfbd0ee36d4c4bb9f5318d0d8ea666 |
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