Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma

Abstract Background CRBP-1, a cytosolic chaperone of vitamin A, is identified in a serious number of cancers; however, its biological role in hepatocellular carcinoma (HCC) needs to be further explored. The aim of our present study is to explore the roles and mechanisms of CRBP-1 in regulating liver...

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Auteurs principaux: Xiangye Liu, Wenhua Shan, Tingting Li, Xiaoge Gao, Fanyun Kong, Hongjuan You, Delong Kong, Shuxi Qiao, Renxian Tang
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/a8e010a05b0c4c8aab6ce3172338d044
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