Visualizing the Potential Impairment of Polymyxin B to Central Nervous System Through MR Susceptibility-Weighted Imaging

Polymyxin B (PMB) exert bactericidal effects on the cell wall of Gram-negative bacteria, leading to changes in the permeability of the cytoplasmic membrane and resulting in cell death, which is sensitive to the multi-resistant Gram-negative bacteria. However, the severe toxicity and adverse side eff...

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Auteurs principaux: Ni Zhang, Lichong Zhu, Qiuhong Ouyang, Saisai Yue, Yichun Huang, Shuang Qu, Runwei Li, Yuanyuan Qiao, Man Xu, Fangfei He, Bin Zhao, Lai Wei, Xiaoai Wu, Peisen Zhang
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/a931a6d3b10d45f095f4fe27b6a6996d
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