Enzymatic ligation of an antibody and arginine 9 peptide for efficient and cell-specific siRNA delivery

Abstract A fusion protein comprising an antibody and a cationic peptide, such as arginine-9 (R9), is a candidate molecule for efficient and cell-specific delivery of siRNA into cells in order to reduce the side effects of nucleic acid drugs. However, their expression in bacterial hosts, required for...

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Autores principales: Yu Ando, Hikaru Nakazawa, Daisuke Miura, Maho Otake, Mitsuo Umetsu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a93f63012e644dfbadfe780137a79059
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