Enzymatic ligation of an antibody and arginine 9 peptide for efficient and cell-specific siRNA delivery
Abstract A fusion protein comprising an antibody and a cationic peptide, such as arginine-9 (R9), is a candidate molecule for efficient and cell-specific delivery of siRNA into cells in order to reduce the side effects of nucleic acid drugs. However, their expression in bacterial hosts, required for...
Guardado en:
Autores principales: | Yu Ando, Hikaru Nakazawa, Daisuke Miura, Maho Otake, Mitsuo Umetsu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a93f63012e644dfbadfe780137a79059 |
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