Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels
Ceramides are a type of sphingolipid (SL) that have been shown to play a role in several metabolic disorders. Here, the authors investigate the effect of SL-production by gut Bacteroides on host SL homeostasis and show that microbiome-derived SLs enter host circulation and alter ceramide production.
Guardado en:
Autores principales: | Elizabeth L. Johnson, Stacey L. Heaver, Jillian L. Waters, Benjamin I. Kim, Alexis Bretin, Andrew L. Goodman, Andrew T. Gewirtz, Tilla S. Worgall, Ruth E. Ley |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a946ac4716d946b782e0ae26fb93f95f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Interactions between the Gut Microbiome and Mucosal Immunoglobulins A, M, and G in the Developing Infant Gut
por: Anders Janzon, et al.
Publicado: (2019) -
Self-Protection against the Sphingolipid Biosynthesis Inhibitor Fumonisin B<sub>1</sub> Is Conferred by a <italic toggle="yes">FUM</italic> Cluster-Encoded Ceramide Synthase
por: Slavica Janevska, et al.
Publicado: (2020) -
Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
por: Hao Q. Tran, et al.
Publicado: (2019) -
Coordination of rapid sphingolipid responses to heat stress in yeast.
por: Po-Wei Chen, et al.
Publicado: (2013) -
Neurodegenerative Disorders: Spotlight on Sphingolipids
por: Frida Mandik, et al.
Publicado: (2021)