Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

Abstract Chronic cerebral hypoperfusion is a major cause of age-related vascular cognitive impairment. A well-characterised mouse model has shown that hypoperfusion results in gliovascular and white matter damage and impaired spatial working memory. In this study, we assessed whether cilostazol, a p...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Akihiro Kitamura, Yasmina Manso, Jessica Duncombe, James Searcy, Juraj Koudelka, Margaret Binnie, Scott Webster, Ross Lennen, Maurits Jansen, Ian Marshall, Masafumi Ihara, Raj N. Kalaria, Karen Horsburgh
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/a99c822285fe43d893ff1f0c5c5d7bd5
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!