Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions

Most phasing programmes for sequencing data work well for genomes with low heterozygosity but drop in performance in regions of high heterozygosity. Here, Kajitani et al. develop the assembler Platanus-allee and demonstrate its utility in de novo assemblies of various genomes and the human MHC regio...

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Auteurs principaux:	Rei Kajitani, Dai Yoshimura, Miki Okuno, Yohei Minakuchi, Hiroshi Kagoshima, Asao Fujiyama, Kaoru Kubokawa, Yuji Kohara, Atsushi Toyoda, Takehiko Itoh
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/a9a7890c7a7f4fc695668d57d1a1ea7c
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spelling	oai:doaj.org-article:a9a7890c7a7f4fc695668d57d1a1ea7c2021-12-02T16:58:00ZPlatanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions10.1038/s41467-019-09575-22041-1723https://doaj.org/article/a9a7890c7a7f4fc695668d57d1a1ea7c2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09575-2https://doaj.org/toc/2041-1723Most phasing programmes for sequencing data work well for genomes with low heterozygosity but drop in performance in regions of high heterozygosity. Here, Kajitani et al. develop the assembler Platanus-allee and demonstrate its utility in de novo assemblies of various genomes and the human MHC region.Rei KajitaniDai YoshimuraMiki OkunoYohei MinakuchiHiroshi KagoshimaAsao FujiyamaKaoru KubokawaYuji KoharaAtsushi ToyodaTakehiko ItohNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rei Kajitani Dai Yoshimura Miki Okuno Yohei Minakuchi Hiroshi Kagoshima Asao Fujiyama Kaoru Kubokawa Yuji Kohara Atsushi Toyoda Takehiko Itoh Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions
description	Most phasing programmes for sequencing data work well for genomes with low heterozygosity but drop in performance in regions of high heterozygosity. Here, Kajitani et al. develop the assembler Platanus-allee and demonstrate its utility in de novo assemblies of various genomes and the human MHC region.
format	article
author	Rei Kajitani Dai Yoshimura Miki Okuno Yohei Minakuchi Hiroshi Kagoshima Asao Fujiyama Kaoru Kubokawa Yuji Kohara Atsushi Toyoda Takehiko Itoh
author_facet	Rei Kajitani Dai Yoshimura Miki Okuno Yohei Minakuchi Hiroshi Kagoshima Asao Fujiyama Kaoru Kubokawa Yuji Kohara Atsushi Toyoda Takehiko Itoh
author_sort	Rei Kajitani
title	Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions
title_short	Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions
title_full	Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions
title_fullStr	Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions
title_full_unstemmed	Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions
title_sort	platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a9a7890c7a7f4fc695668d57d1a1ea7c
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Platanus-allee is a de novo haplotype assembler enabling a comprehensive access to divergent heterozygous regions

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