Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation
Cancer cells are characterised by abnormalities in the number of centrosomes and this phenotype is linked with tumorigenesis. Here the authors report centriole length deregulation in a subset of cancer cell lines and suggest a link with subsequent alterations in centriole numbers and chromosomal ins...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/a9b31e151bf34283b9c2a8077242da36 |
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