Distinct Metabolomic Signatures in Preclinical and Obstructive Hypertrophic Cardiomyopathy

Distinct Metabolomic Signatures in Preclinical and Obstructive Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy (HCM) is a common inherited heart disease with poor risk prediction due to incomplete penetrance and a lack of clear genotype–phenotype correlations. Advanced imaging techniques have shown altered myocardial energetics already in preclinical gene variant carriers. To dete...

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Bibliographic Details
Main Authors: Maike Schuldt, Beau van Driel, Sila Algül, Rahana Y. Parbhudayal, Daniela Q. C. M. Barge-Schaapveld, Ahmet Güçlü, Mark Jansen, Michelle Michels, Annette F. Baas, Mark A. van de Wiel, Max Nieuwdorp, Evgeni Levin, Tjeerd Germans, Judith J. M. Jans, Jolanda van der Velden
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
metabolomics
hypertrophic cardiomyopathy
disease signature
disease stage
serum
biomarker
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/a9ba77202bd64ddd8d0b7f6a3dbc9ef4
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