Microenvironment-derived factors driving metastatic plasticity in melanoma

Phenotype switching is a form of plasticity that allows melanoma cancer cells that leave the primary tumour to invade secondary sites, to switch from an invasive to a proliferative state. Here the authors identify EDN3, and its synthetic enzyme ECE2, as a regulator of melanoma plasticity in the micr...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Isabella S. Kim, Silja Heilmann, Emily R. Kansler, Yan Zhang, Milena Zimmer, Kajan Ratnakumar, Robert L. Bowman, Theresa Simon-Vermot, Myles Fennell, Ralph Garippa, Liang Lu, William Lee, Travis Hollmann, Joao B. Xavier, Richard M. White
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/a9ccb537f389465d997a19a77c63d6c9
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!