Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection

Abstract The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in the neonatal rat. Gastrointestinal (GI) colonization of two-day-old (P2) rats leads to invasion of the blood within 48 h of initiation of colonization; pups become progressively less susce...

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Bibliographic Details
Main Authors: George M. H. Birchenough, Fatma Dalgakiran, Luci A. Witcomb, Malin E. V. Johansson, Alex J. McCarthy, Gunnar C. Hansson, Peter W. Taylor
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/a9cf43c446994812b02c7c23a91027a5
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