Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection

Abstract The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in the neonatal rat. Gastrointestinal (GI) colonization of two-day-old (P2) rats leads to invasion of the blood within 48 h of initiation of colonization; pups become progressively less susce...

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Auteurs principaux: George M. H. Birchenough, Fatma Dalgakiran, Luci A. Witcomb, Malin E. V. Johansson, Alex J. McCarthy, Gunnar C. Hansson, Peter W. Taylor
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/a9cf43c446994812b02c7c23a91027a5
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