Regulatory properties of vitronectin and its glycosylation in collagen fibril formation and collagen-degrading enzyme cathepsin K activity

Abstract Vitronectin (VN) is a glycoprotein found in extracellular matrix and blood. Collagen, a major extracellular matrix component in mammals, is degraded by cathepsin K (CatK), which is essential for bone resorption under acidic conditions. The relationship between VN and cathepsins has been unc...

Full description

Saved in:
Bibliographic Details
Main Authors: Kimie Date, Hiromi Sakagami, Kei Yura
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/a9d05c6eb7f74908a19bfe686df18e63
Tags: Add Tag
No Tags, Be the first to tag this record!